GENE SELECTION BASED CANCER CLASSIFICATION WITH ADAPTIVE OPTIMIZATION USING DEEP LEARNING ARCHITECTURE



Genome-wide identification of Bcl11b gene targets reveals role in brain-derived neurotrophic factor signaling.

Mains Block Cover B-cell leukemia/lymphoma 11B (Bcl11b) is a transcription factor showing predominant expression in the striatum.To date, there are no known gene targets of Bcl11b in the nervous system.Here, we define targets for Bcl11b in striatal cells by performing chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) i

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Generation and characterization of Kctd15 mutations in zebrafish.

Potassium channel tetramerization domain containing 15 (Kctd15) was previously found to have a role in early neural crest (NC) patterning, specifically delimiting the region where NC markers are expressed via repression of transcription factor AP-2a and inhibition of Wnt signaling.We used transcription activator-like effector nucleases (TALENs) to

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